Assessment One PHMY803

Note: There is a choice of two assignment options

Task overview:

To critically review research evidence to support the analysis of pharmacology science, benefits and risks of medications used in the management of a specified condition or clinical indication.

Learning Outcomes Assessed in this Assignment

1. Examine the pharmacokinetics and pharmacodynamics of selected drugs.
2. Analyse and apply pharmacology science, clinical guidelines, and research evidence to the therapeutic use of drugs.
3. Present work at the appropriate academic standard

Option One Instructions

1. Select a condition or clinical indication that you see patients present with in your clinical practice.

2. Select a medication regimen of 3-4 medications that are used to manage or treat that condition either as a maintenance regimen or with maintenance plus added medication for an acute flare, exacerbation or presentation.

3. If your clinical practice is frontline paramedic practice, or emergency clinical practice then you can select a condition you commonly see patients present with that you need to treat in the acute phase or with current exacerbation of symptoms. In this situation you can include medications from the existing regimen as well as the medications that you administer in the current presentation to make up the 3- 4 medications.

4. Provide a brief overview of the pathophysiology – just enough to set the scene for a multiple medication regimen (LO1).

5. Analyse each of the 3-4 medications in the regimen in terms of the
pharmacodynamics, any significant pharmacokinetics that you need to be mindful of, contraindications and any significant adverse effects (LO1, LO2).

6. Explain the synergistic benefits (or lack of benefit) achieved by these medications being co-prescribed in a regime (LO1, LO2).

7. Critically analyse the additional risks posed by the co-prescription of multiple medications in a regime (LO1, LO2).

8. Support your critical analysis with at least four quality, peer-reviewed research articles, and clinical guidelines or procedures (LO2, LO6).

9. Include an introduction and conclusion to your assignment (LO6)

Option Two Instructions

1. Select a condition or clinical indication that you see patients present with in your clinical practice.

2. Select 3-4 medications that can be prescribed as alternatives for treatment options for this condition or clinical indication.

3. Provide a brief overview of the pathophysiology of the condition – just enough to set the scene for a comparison of the medications for managing the condition or clinical indication (LO1).

4. Critically compare each of 3-4 medications in the regimen in terms of the
pharmacodynamics, significant pharmacokinetics, contraindications and adverse effects (LO1, LO2).

5. Critique clinical guidelines on prescription of these medications against research evidence for each the medications for this condition or clinical indication (LO1, LO5).

6. Support your critique with at least four quality, peer-reviewed research articles, and clinical guidelines or procedures (LO2, LO6).

7. Make a justified recommendation for the prescription of one of the medications over the others (LO1, LO2.

8. Include an introduction and conclusion to your assignment (LO6)

Format and referencing instructions

1. Reference List: Include the four research articles and all other literature and
clinical guidelines or professional websites used to develop your thinking and
writing. Use APA 7th edition format. https://aut.ac.nz.libguides.com/APA7th.

2. Declare any use of AI (Grammarly, Studiosity, Co-pilot, Chat GPT etc) on your
Academic Integrity declaration to the front page of your assignment. You are not penalised for the appropriate use of these tools as per the PHMY803 generative AI guidelines and within the AUT guidelines.
https://canvas.aut.ac.nz/courses/7624/pages/genai-at-aut

3. You can include up to two original tables or diagrams (or one of each) that you developed that do not count towards your word count.

4. Cite the reference sources for the details used to develop the table or diagram. Make sure you refer to the table or diagram in the written text of the assignment to give context to it.

5. We do not award any marks for diagrams or tables from reference sources – we only mark the standalone explanations around these in the written text of your assignment.

Submission Information

Submission: Electronic submission through the PHMY803 Canvas Course Assignment site. The submission will automatically submit through Turnitin -two attempts at submission with one return of a Turnitin report